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In quest of the origin of ancient northern city of China: An implication from the Book of Odes

DAI Fudong

Frontiers of Structural and Civil Engineering 2007, Volume 1, Issue 4,   Pages 389-392 doi: 10.1007/s11709-007-0052-9

Abstract: Sorting out some paragraphs in (collection of the earliest poetry in China), this paper makes analysis of the formation, construction process and technology of the ancient northern city of China. Relevan

Keywords： analysis     construction     formation     collection     paragraphs    

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Recent transmission of Mycobacterium tuberculosis in China: the implication of molecular epidemiology

Chongguang Yang, Qian Gao

Frontiers of Medicine 2018, Volume 12, Issue 1,   Pages 76-83 doi: 10.1007/s11684-017-0609-5

Abstract:

Tuberculosis (TB) has remained an ongoing concern in China. The national scale-up of the Directly Observed Treatment, Short Course (DOTS) program has accelerated the fight against TB in China. Nevertheless, many challenges still remain, including the spread of drug-resistant strains, high disease burden in rural areas, and enormous rural-to-urban migrations. Whether incident active TB represents recent transmission or endogenous reactivation has helped to prioritize the strategies for TB control. Evidence from molecular epidemiology studies has delineated the recent transmission of ( ) strains in many settings. However, the transmission patterns of TB in most areas of China are still not clear. Studies carried out to date could not capture the real burden of recent transmission of the disease in China because of the retrospective study design, incomplete sampling, and use of low-resolution genotyping methods. We reviewed the implementations of molecular epidemiology of TB in China, the estimated disease burden due to recent transmission of strains, the primary transmission of drug-resistant TB, and the evaluation of a feasible genotyping method of strains in circulation.

Keywords： tuberculosis     recent transmission     molecular epidemiology     China    

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Expression and clinical implication of PRL-1 and PRL-3 in transitional cell carcinoma of bladder

Bin HAO, Changwei LIU, Huixiang LI

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 197-203 doi: 10.1007/s11684-009-0036-3

Abstract: The mRNA and protein expression of phosphatase of regenerating liver 1 (PRL-1) and phosphatase of regenerating liver 3 (PRL-3) in transitional cell carcinoma of bladder (BTCC) and normal epithelia of bladder was investigated, and the relationship between the BTCC and pathological changes was clarified. The expression of PRL-1 and PRL-3 mRNA was detected by using reverse transcription polymerase chain reaction (RT-PCR) in 30 cases of BTCC and 10 cases of normal bladder, and the expression of PRL-1 and PRL-3 protein was checked by using immunohistochemistry in 30 cases of BTCC and 15 cases of normal bladder. The expression levels of PRL-1 and PRL-3 mRNA and protein were higher in BTCC than those in normal bladder epithelia ( <0.05). The increased expression of PRL-1 and PRL-3 mRNA and protein was detectable in deep invasion and metastasis of BTCC ( <0.05). There was no correlation between the expression of PRL-1 and PRL-3 and gender, age or recurrence of BTCC (all >0.05). A significantly positive correlation was found between PRL-1 and PRL-3 in BTCC ( <0.05). PRL-1 and PRL-3 are expressed consistently and may contribute to the growth, differentiation, invasion and metastasis of BTCC.

Keywords： transitional cell carcinoma of bladder     phosphatase of regenerating liver 1     phosphatase of regenerating liver 3     reverse transcription polymerase chain reaction     immunohistochemistry    

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Development Trends and Implication in Marine Engineering and Technology

Task Force for the Study on Development Strategy of China’s Marine Engineering and Technology Comprehensive Research Group

Strategic Study of CAE 2016, Volume 18, Issue 2,   Pages 126-130 doi: 10.15302/J-SSCAE-2016.02.016

Abstract:

The paper examines current state and trends of the marine engineering and technologies around the world and attempts to extrapolate lessons for China’s development efforts. The major characteristics and tendency of the world ocean development come in the form of advanced equipment and technology, which are used as the main force for promoting ocean resource exploitation, ocean energy exploration and extraction as an important industry to the world's countries; living marine resources as a competitive focus, marine pollution management and prevention as the priority issue, and land-sea integration engineering as an important part for marine development. In-depth analysis of the aforementioned characteristics and trends allows us reach a list of important recommendations. Therefore China should strengthen its awareness of national ocean policy issues and enhance ocean development position as part of its the national development strategy; promote science and technology innovation; optimize marine industrial infrastructure and vigorously support emerging marine industries; improve its comprehensive management system and establish a mechanism for the coordinated development; strengthen protection of resources and the environment and keep sustainable exploitation on resource.

Keywords： marine engineering     marine science and technology     development trends     implication    

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Pathogenesis of pandemic H1N1 2009 influenza virus infection and the implication on management

Kelvin Kai-Wang TO FRCPath, Iris Wai-Sum LI FRCP, Ivan Fan-Ngai HUNG FRCP, Vincent Chi-Chung CHENG FRCPath, Kwok-Yung YUEN MD,

Frontiers of Medicine 2010, Volume 4, Issue 2,   Pages 147-156 doi: 10.1007/s11684-010-0030-9

Abstract: The pandemic H1N1 2009 influenza virus has caused the first influenza pandemic of the 21st century, leading to disproportionate fatalities in the low-risk population despite the generally mild nature of the illness. Advances in sci

Keywords： influenza A virus     H1N1 subtype     pandemic     pathogenesis     virulence factors     immunity     management     antiviral    

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Current Research Status of Heterodera glycines Resistance and Its Implication on Soybean Breeding Review

Guiping Yan,Richard Baidoo

Engineering 2018, Volume 4, Issue 4,   Pages 534-541 doi: 10.1016/j.eng.2018.07.009

Abstract:

Heterodera glycines (i.e., soybean cyst nematode, SCN) is the most damaging nematode pest affecting soybean crop worldwide. This nematode is managed by means of crop rotation with selected resistant sources. With increasing reports of virulent SCN populations that are able to break the resistance within commonly used sources, there is an increasing need to find new sources of resistance or to broaden the resistance background. This review summarizes recent findings about the genes controlling SCN resistance in soybean, and about how these genes interact to confer resistance against SCN in soybean. It also provides an update on molecular mapping and molecular markers that can be used for the mass selection and differentiation of different resistance lines and cultivars in order to expedite conventional breeding programs. In-depth knowledge of SCN parasitism proteins and soybean resistance responses to the pathogen is critical for the diversification of resistant sources through gene modification, gene stacking, or incorporation of novel sources of resistance through backcrossing or genetic engineering.

Keywords： Soybean cyst nematode     Heterodera glycines     Resistance     Molecular breeding    

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Title Author Date Type Operation

In quest of the origin of ancient northern city of China: An implication from the Book of Odes

DAI Fudong

Journal Article

Recent transmission of Mycobacterium tuberculosis in China: the implication of molecular epidemiology

Chongguang Yang, Qian Gao

Journal Article

Expression and clinical implication of PRL-1 and PRL-3 in transitional cell carcinoma of bladder

Bin HAO, Changwei LIU, Huixiang LI

Journal Article

Development Trends and Implication in Marine Engineering and Technology

Task Force for the Study on Development Strategy of China’s Marine Engineering and Technology Comprehensive Research Group

Journal Article

Pathogenesis of pandemic H1N1 2009 influenza virus infection and the implication on management

Kelvin Kai-Wang TO FRCPath, Iris Wai-Sum LI FRCP, Ivan Fan-Ngai HUNG FRCP, Vincent Chi-Chung CHENG FRCPath, Kwok-Yung YUEN MD,

Journal Article

Current Research Status of Heterodera glycines Resistance and Its Implication on Soybean Breeding

Guiping Yan,Richard Baidoo

Journal Article